OneTreck®: Precision Medicine for All, Everywhere
Invest in an Innovative and Scalable company
Imagine a technology so versatile that it can be deployed both on Earth and in space exploration, meeting health needs in underserved areas while enriching pharmaceutical R&D with unprecedented data on unmet needs.
This is the promise of OneTreck®
with a clear goal: to bring precision medicine to everyone, everywhere.
An Ecosystem of Medical Innovation: Two Products, One Global Impact
Manta Voyager
This clinical decision support software (CDSS) embedded on a laptop both performs diagnostics and suggests treatments based on patient data in underserved medical areas, while also collecting field data in these environments.
Manta Pharma
Leverages Manta Voyager’s data for clinical and preclinical R&D, enabling the identification of mechanisms of action (MOA), disease progression biomarkers, responsive patient profiles, and opportunities for indication expansion or rescue in clinical trials.
The interaction between these two products creates a unique ecosystem where every field-collected data point enriches R&D, and vice versa, to offer increasingly precise and adapted care.
For a biotech, partnering with OneTreck® is about giving its lead therapeutic the same chances as those developed by big pharma and securing the highest valuation for its investors.
For Biotechs in Preclinical Development
Accelerated R&D
By rapidly identifying progression biomarkers and mechanisms of action (MOA)
Manta Pharma reduces development time by over 2 years, enabling faster entry into clinical
phases.
Reduced Development Costs
This optimized preclinical approach helps biotechs cut expenditures by 20%
Achieving savings of €0.5 to €1.5 million per therapeutic candidate by identifying
promising molecules
and their mechanisms of action early on, as well as exhaustively identifying relevant
indications and
avoiding resource allocation to non-viable candidates.
For Biotechs in Clinical Phases
Enhanced Precision & Personalization of Clinical Trials
Manta Pharma combines traditional data science tools with the creation of digital twins for
each patient
incorporating real-world data and underlying comorbidities.
This approach enables the identification of progression and treatment response signatures in a
highly
integrative and precise way, based on over 45,000 observables—more than twice the current
standards in
multivariate analyses.
Rescue or Indication Expansion
Manta Pharma can reveal new indications for existing molecules, facilitating either the rescue
of at-risk
clinical trials or the expansion of indications for broader market opportunities.
This strategy maximizes revenue potential while optimizing costs, directly contributing to
increased biotech
valuation—achieving a net financial gain of over €15 million.
Our technology is based on a unique set of several thousand
disease
progression models, recreating patient pathways to achieve unmatched personalization that
accounts for
patient specificity in clinical trials.
Through comprehensive causality analysis, we identify the true response factors, providing
treatments
tailored to each patient's unique characteristics.
Finally, the continuous integration of real-world data, directly sourced from patients' daily
lives, grounds
our technology in real-life care practices, ensuring even more precise treatments.
OneTreck® primarily targets biotechs and generates revenue through a fee-for-service model for Manta Pharma, with strategic partnerships, including joint ventures (JVs) that may include a flat fee and potentially royalties on therapeutic development.
For Manta Voyager, we have developed an innovative business model that enables optimized market penetration and remains adaptable to the specific needs of each environment.
OneTreck® is a health deeptech spin-off from the CNRS, based in the French Alps in Grenoble, often
referred to as
the "French Silicon Valley."
This strategic location allows us to benefit from unique synergies with research institutes and
technology
clusters in the region, reinforcing our mission to bring precision medicine to the widest audience.
The OneTreck® team brings advanced expertise in directed graph technology, physiology, and
biomedical data
processing.
Our integration within this cutting-edge ecosystem includes close ties with the MIAI (AI)
excellence cluster and the medical device ecosystem, which supports our capacity for innovation and
accelerates
the development of next-generation precision medicine solutions.
